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These numbers assume that youre a healthy adult with a healthy gut, and if youve got IBD or a current deficiency, then you may be advised to take many times that amount

If youre using this for rejuvenation (as opposed to preventative maintenance), it is recommended to do at monthly intervals for a total of 3-4 treatments, then biannually from there

As of June 2026, the FDA's December 2024 Pharmacy Compounding Advisory Committee evaluation concluded that the criteria weighed against placing AOD-9604 (free base) or AOD-9604 acetate on the 503A Bulks List, and AOD-9604 is currently listed as Nominated but Withdrawn from FDA Category 2

Regular monitoring of B12 levels is typically recommended for those receiving ongoing treatment

Dr Sudhir Kumar MD DM (@hyderabaddoctor) January 23, 2023 As such, we reached out to experts to understand the role of vitamin B12, its deficiency, and whether it is possible to overdose on supplements or injections

It has not been shown to boost energy, endurance, or performance in people with adequate B12 status