Interestingly, all of the genes exhibited a significant negative correlation with SLE scores (SLEDAI), suggesting the critical role of these five genes in alleviating the progression of SLE
10.1038/mp.2013.101 27 CastejonA
Tretinoin is an FDA-approved retinoid with the strongest clinical evidence for photoaging
Psychostimulants have been reported to induce long-term extracellular and intracellular neurochemical damage primarily via glutamate-mediated pathways in dopaminergic reward systems, thereby modifying neuronal viability and neuroplasticity [31]

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