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antihistamines (e.g., chlorpheniramine, due to sedation and anticholinergic load), certain benzodiazepines and sedatives (possible enhanced sedative or hypotensive effects), and sympathomimetics (risk of hypertension) have all been noted as interactions in drug databases

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It is important to thoroughly massage the treated areas for five minutes, five times daily, for five days to seven days after each treatment, to allow for the even distribution of the product and to ensure natural-looking results

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