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They are consistent with the known side effect profile of GLP-1 receptor agonists already approved in the UK (see, for example, the Wegovy Summary of Product Characteristics, available via the electronic Medicines Compendium)

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The mounting evidence that GLP-1 RA effects are not limited to a single organ and have a variety of effects on health across a range of organ systems or organ-specific health conditions is a strong recommendation for their use to assist those who are non-obese but otherwise metabolically healthy to improve overall health

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