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Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation

If tirzepatide can reduce intracranial pressure enough to resolve headaches in IIH, it is plausible that it can reduce pressure enough to lower the migraine threshold in people without a formal IIH diagnosis

Headaches Headaches may occur, especially during the first week

While this isnt among the most common side effects, changes in blood sugar, immune response, or the vaginal microbiome may make some people more prone to symptoms like itching, burning, or unusual discharge

The gut microbiota during a behavioral weight loss intervention

Lingvay I, et al