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References World Health Organisation, WHO Coronavirus (COVID-19) dashboard

The body excretes excess water-soluble B12 in urine

Studies have found that high NNMT expression promotes the release of inflammatory factors in adipose tissue, and NNMTi can effectively alleviate adipose inflammation and improve the microenvironment by inhibiting NNMT

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This means they can penetrate the blood-brain (or blood-SCF) barrier and reach neurons directly, enabling the drug to exhibit organ-specific combined effects in the brain

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