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Vomiting occurs in approximately 24% of Wegovy users, though it is generally less common than nausea and tends to correlate with nausea severity

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This directly complicates patient screening and enrollment, leads to substantially lower overall expected efficacy compared with patients harboring upstream genetic defects (such as POMC deficiency) [56] , and results in a low statistical success rate in large-scale trials

doi: 10.1016/j.biopha.2018.08.088 23 AstJArvanitiAFineNHFNasteskaDAshfordFBStamatakiZet al

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The claim: Eating it 15 to 30 minutes before a meal helps you feel fuller faster, cut cravings, and reduce calorie intake