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NK1R antagonists or genetic deletion of NK1R induces anxiolytic and antidepressant-like effects in animal models (Teixeira et al., 1996

Mechanistically, L2HG acts as a metabolic-epigenetic regulator that inhibits 2-oxoglutarate-dependent dioxygenases, induces histone hypermethylation, and remodels chromatin accessibility to activate an ATF3-dependent transcriptional program

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Modo de uso: La dosis depende de varios factores como ser el peso corporal, el nivel de sobrepeso si es que existe, el tipo e intensidad de la actividad fsica que realiza