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Contrave is not appropriate for patients with seizure disorders (bupropion lowers the seizure threshold), eating disorders such as bulimia or anorexia, current opioid use or opioid dependence (naltrexone blocks opioid receptors), uncontrolled hypertension, patients taking MAO inhibitors, or women who are pregnant or planning to become pregnant

Wilton et al., 2016

Ready-to-use- food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial

E., Jeppesen, O

Caution:Do not use if you are pregnant or breastfeeding

Leveraging this duality provides a conceptual framework for identifying redox-defined liabilities and developing next-generation therapies that exploit metabolic and oxidative imbalances in cancer and other diseases