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Patients with a mean baseline HbA1c of 8.1% (range 6.5%-10.7%) were randomized to receive either SYMLIN or placebo, both administered before major meals as add-on to insulin therapy

These results are partially relevant from a clinical perspective, as diet remains a key component of obesity treatment

Sustained, low-level receptor activation could help preserve neuronal glucose utilization and synaptic functioncritical to long-term cognitive health in women after menopause, when estrogens neuroprotective effect wanes

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