Laios K
H&E staining revealed signs of neuronal damage, such as cell shrinkage and pyknosis, particularly in the CA1 and dentate gyrus (DG) regions (Figure 2A)
Severe, persistent vomiting that prevents adequate fluid intake, intense abdominal pain, or signs of gastroparesis (severe gastric retention) warrant medical evaluation
Studies also have relayed its role in appetite control and glucose management
Patients with certain genetic predispositions may achieve robust weight loss with minimal dietary adjustment, while others benefit from more intentional nutrition changes to maximize their medication's effect
James Chao, a board-certified physician specializing in medical weight loss and co-founder of VedaNu Wellness, notes that patients who lose weight without dietary guidance can lose between 15% and 40% of that weight from lean body mass