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doi: 10.1016/j.plaphy.2011.10.020 40 KirlyZ.BarnaB.KecsksA.FodorJ

doi: 10.1101/2023.06.22.546075 [DOI] [PMC free article] [PubMed] [Google Scholar] 66.Sun F, Zhou J, Dai B, Qian T, Zeng J, Li X, et al

In terms of valence (pleasure) and arousal (motivation), GLP-1 lowers the arousal or urgency triggered by food cues while boosting the positive valence of actually eating the food, thereby signaling the brain, "This is enough, youre full." These neuroimaging findings give a concrete mechanism for the subjective reports of reduced cravings on GLP-1 therapy

This combination effectively targets the two primary components of body composition: fat reduction and muscle maintenance

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