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Although previous studies, including our own, have reported linear disulfide-based sensors capable of bypassing GSH interference under specific experimental conditions, it is now clear that over extended timescales and within the more complex intracellular redox milieu, these molecules fail to maintain selectivity for a defined redox species 21,22,61,65,66,67
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Brunmark, A
Interestingly, in two small studies, those with metabolic comorbidities treated with a FAE showed improvement in metabolic syndrome-associated biomarkers 27 and in endothelial function
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