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Primary pulmonary hypertension: Phentermine has been associated with primary pulmonary hypertension, a rare but often fatal condition that may present with shortness of breath, chest pain, passing out, or leg swelling

Psychological factors influence real-world outcomes even when pharmacological mechanisms are superior

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Long-term mechanistic data on extending healthspan in humans is still emerging

The therapies don't interfere with each other because they operate through unrelated pathways