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When Constipation Signals a Need to Adjust Your Treatment Severe constipationdefined as no bowel movement for more than 3 days, accompanied by abdominal pain, bloating, or nausearequires immediate contact with your prescriber

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Abbreviations ACF : Aberrant crypt foci ASD : Autism spectrum disorder BDNF : Brain-derived neurotrophic factor CEA : Carcinoembryonic antigen CIP-SeNPs : Inulin-type fructan CIP70-1 based selenium nanoparticles CMPA : Cows milk protein allergy CRP : C-reactive protein DMH : 1,2-Dimethylhydrazine DP : Degree of polymerization FFAR2 : Free fatty acid receptor 2 FFAR3 : Free fatty acid receptor 3 GIT : Gastrointestinal tract GLP-1 : Glucagon-like peptide-1 GPR43 : G-protein coupled receptor 43 GLUT4 : Glucose transporter type 4 HbA1c : Hemoglobin A1c HDL-C : High-density lipoprotein cholesterol L-cell : Specialized enteroendocrine cell in the gut producing hormones like GLP-1 and PYY LDL-C : Low-density lipoprotein cholesterol PLON-R : Oral Language Task of Navarra-Revised PYY : Peptide YY SCFAs : Short-chain fatty acids TAG : Triacylglycerol TNF- : Tumor necrosis factor-alpha References Gibson GR, Roberfroid MB

Results may begin to surface within weeks

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