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The GPX family contains eight members (GPX1-GPX8), of which GPX1-GPX4 and GPX6 (human) members have an active center of selenocysteine, which is an important selenoprotein in mammals (Table 1)

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pretreated with aqueous-methanolic(Compositae) (500 mg/kg) also had the hepatoprotective effects by reducing ALT and AST levels, and inhibiting microsomal drug-metabolizing enzymes (Gilani and Janbaz, 1995a)