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[DOI] [PubMed] [Google Scholar] Rossi D, Zlotnik A (2000) The biology of chemokines and their receptors
There's one important safety consideration: people with G6PD deficiency (a genetic enzyme condition) should avoid glutathione therapy entirely, as it can cause serious complications
Studies with mutants and transgenic plants over- or under-expressing enzymes or metabolites of the AsA-GSH pathway have proved very well the co-relation between this pathway and stress tolerance (Gill and Tuteja, 2010)
Sulzer and Zecca, 2000
All of these factors can contribute to poor production of glutathione (or of the enzymes that help glutathione to do its work), and many also deplete the GSH that the cells produce (by converting it into GSSG)
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