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The therapeutic landscape has evolved quickly with the introduction of more potent agents, including semaglutide and the dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist tirzepatide, which have demonstrated superior efficacy in randomized controlled trials [1, 5, 6]

(10) In cell cultures of fibroblasts, which are the main type of cell producing collagen in tissues, including ligaments, the peptide appeared to markedly support fibroblast outgrowth, migration, and spreading

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