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Through cleavage of dynamic phenylboronic ester bonds under ROS stimulation 62 , the hydrogel demonstrated ROS-sensitive drug release behavior, as evidenced by the 90% cumulative release of D-CuP within 72 h under H 2 O 2 stimulation (Fig

We can also perform additional tests to evaluate the presence of excess heavy metals and NAD+ levels

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8 Future challenges and directions Although numerous studies have demonstrated the potential of IGF-1 in advancing tendon treatment strategies, significant challenges remain in developing an effective IGF-1-based therapy for tendon regenerative healing