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In the current HepG2 cell model, in which prolonged exposure is not feasible, the use of relatively high QI concentrations in a short timeframe allows for the identification of underlying mechanisms and pathways, as has been done previously in similar studies with hepatic toxicants (Tafazoli and OBrien, 2009

[DOI] [PMC free article] [PubMed] 112.You J, Juhng S, Song J, Park J, Jang M, Kang G, et al

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Injections bypass the gut and correct deficiency