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Without those internal hunger cues, Joy explained, youre more likely to skip meals or reach for unhealthy convenience foods

Clinical evidence is limited but increasing

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For example, metabolic disorders like type 2 diabetes involve a complex interplay between pancreatic, hepatic, adipose, and immune cells (187), while cancer progression and drug resistance are increasingly linked to interactions between tumor cells, stromal fibroblasts, immune infiltrates, and endothelial components (188, 189)