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Protein: Higher intake prevents the muscle loss that slows metabolism Studies show that a lot of body weight lost on semaglutide comes from lean muscle mass
Previous CADTH submissions using the Institute of Health Economics cohort model have identified issues for the face validity of the model that do not appear to have been fully addressed in the current submission
If your swelling lasts more than two to three weeks without improvement, or if its getting worse, contact your healthcare provider to rule out infection or other issues
Yes, the active ingredient in Ozempic can cause side effects
In one real-world study, patients on tirzepatide lost 15.3% of their body weight at 12 months, compared to 8.3% for those on semaglutide
Obtain comprehensive baseline labs: TSH, free T4, free T3 Thyroid antibodies (TPO and thyroglobulin if not previously checked) Complete metabolic panel HbA1c and fasting glucose Lipid panel Vitamin D and B12 (commonly deficient in hypothyroidism) During Treatment When to Contact Your Provider Reach out if you experience: Unusual or worsening fatigue not explained by semaglutide initiation New or returning brain fog or cognitive difficulty Constipation that does not improve with typical measures Heart rate changes (especially sustained bradycardia) Cold intolerance or dry skin changes Weight loss plateau despite medication adherence Hair loss beyond what is expected with weight loss Mood changes including depression or anxiety Semaglutide Alternatives for Hypothyroid Patients For patients who cannot take semaglutide or prefer alternatives, several options exist: Tirzepatide (Mounjaro/Zepbound): Dual GLP-1/GIP agonist with potentially greater weight loss
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