Along its length, the enteroendocrine cells (EECs) constitute a complex endocrine organ that communicates with the central nervous system (CNS) and the enteric nervous system (ENS) to orchestrate the homeostatic balance of the body in response to the GI luminal content
Cost concerns can be addressed through patient assistance programs offered by pharmaceutical manufacturers
It was originally developed for type 2 diabetes management (Ozempic) but showed such dramatic weight loss effects that the FDA approved a higher-dose formulation for chronic weight management (Wegovy)
It has since become common practice to use phentermine for chronic weight management
Ongoing Support STEP 3 Physician guidance for dose adjustments, side-effect management, and long-term success
Liraglutide, semaglutide and tirzepatide are European Medicines Agency approved to improve metabolic control in T2DM and to decrease weight in persons with obesity [body mass index (BMI) 30 kg/m 2 ] or with overweight (BMI 27 kg/m 2 ) associated with weight-related comorbidities such as hypertension, dyslipidaemia, CVD and others