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Manfaat glutathione untuk kulit tidak hanya berkaitan dengan efek mencerahkan, tetapi juga perannya dalam menjaga sel kulit tetap sehat
Oxidation of cysteine residues can result in a wide range of redox-based, post-translational modifications, including S-nitrosylation, S-glutathionylation and sulfinic acid, sulfenic acid and disulfide formation 22,23 , which can generate conformational changes in protein structure and subsequent modulation of protein activity 24
Moreover, due to the difference in animal models and research species, it is not reliable to extrapolate results from one environment to the other
Several studies have shown that the expression and/or activity of CBS is tightly regulated and strongly depends on the redox state of the cell (Mosharov et al., 2000
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