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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Coskun T, Heise T, DeVries J, Urva S, Li J, Pratt EJ, et al
We next observed that at 0.5% O 2 hypoxia, proliferation of HeLa cells expressing LUC was slower compared to that at 21% O 2 but Cr GPDH expression allowed substantial growth rescue after two days following induction of Cr GPDH expression with Dox ( Figure 4f-h )
The maintenance of glycolysis in xCT high cancer cells is essential for constituting a potential treatment strategy to induce ferroptosis [Figure 2A]