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Excess iron and the resulting oxidative stress can directly damage oocytes, sperm, and developing embryos, impairing fertilization and early development [102]

Burmaoglu S., Ozcan S., Balcioglu S., et al., Synthesis, Biological Evaluation and Molecular Docking Studies of BisChalcone Derivatives as Xanthine Oxidase Inhibitors and Anticancer Agents, Bioorganic Chemistry 91 (2019): 103149, 10.1016/j.bioorg.2019.103149

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We observed a high variability in 7,8-DHF brain distribution