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Extended validation DNG (PF-06882961) improves glucose tolerance and plasma insulin levels in genOhGLP-1R mouse model 13 genOhGLP-1R or WT mice were injected with DNG or vehicle and 15 minutes later administered 40% dextrose at 2g/kg

This receptor is normally activated by ghrelin, the hunger hormone, which also plays a key role in GH regulation

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GLP-1 agonists bind to GLP receptors in the human body and trigger the effects listed above

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