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Tirzepatide has been shown in clinical trials to reduce the risk of cardiovascular events at various doses, suggesting a potential treatment option for patients who are obese or overweight [2]

DISC1 regulates neurogenesis via modulating kinetochore attachment of Ndel1NDEL1/Nde1 during mitosis

Vitamin D, 1-alpha-hydroxylase (vitamin D-binding protein), and VDR are found in various areas of the central nervous system

Furthermore, the telomeres of white blood cells in individuals suffering from diabetic nephropathy also exhibit significant shortening

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Natural compounds such as resveratrol and pterostilbene have shown inhibition of ferroptosis in cardiomyocytes via the SIRT1/p53 and SIRT1/Glycogen Synthase Kinase-3 (GSK-3)/GPX4 signaling pathways, improving cardiac function and reducing cardiac remodeling in heart failure models (Zhang et al., 2023b