negevensis encodes a virus tegument-like DUB, Josephin-like DUBs and ULPs, of which one enzyme even reacts with an activity-based probe of ISG15 26,27,28,29
They observed that chronic depletion of mucosal GSH by buthionine sulfoximine (BSO), a specific inhibitor of GCL[47], caused severe degeneration of epithelial cells from jejunum and colon, which was prevented by oral GSH or GSH monoester
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