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Subcutaneous administration is the standard for this compound

Many patients benefit from logging meals, exercise, and blood sugar readings to identify individual triggers

Mechanistically, TMAO may contribute to electrophysiological dysfunction by activating the protein kinase R-like endoplasmic reticulum kinase (PERK)/IRE1 axis, leading to increased atrial remodeling and subsequent arrhythmogenesis [62]

10.1038/s41584-018-0111-8 10 LiX.SunY.-Q.HuangQ.-L.ZhangZ.-J.ShiL.-Q.TangJ.-F.et al (2025a)

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Side effects are broadly similar for both