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GLP-1 and other medications of the same class (GLP-1Ras) have an overall favorable risk/benefit profile for qualified candidates, meaning that you can expect optimal results with minimal risk

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While less common than other methods, it can be effective for certain cases

doi: 10.1371/journal.pone.0105478 193 NewellM

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Retrospective studies of GLP1 therapy support the role of structured exercise programs, for example, 360 min/week with an emphasis on strength exercises to preserve fatfree mass [169]