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When activated, it can influence multiple intracellular signalling cascades

An impaired gut barrier allow abnormal translocation of microbial metabolites and structural components into the bloodstream, which may then reach the brain barriers (Leigh et al., 2023)

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Avoid High-sugar Foods & Alcohol : These increase oxidative stress and reduce antioxidant levels in the body

This research explores a novel therapeutic avenue by targeting the brains renin-angiotensin system (RAS) and its interaction with the hepatocyte growth factor (HGF)/c-Met receptor system [2]

This modification in the protein structure ensures a reduced binding affinity of IGF-1 LR3 for IGF-binding proteins in comparison to IGF-1 [6]