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Through the ERK1/2 pathway (Ju et al., 2017), the PI3KAKT pathway (Huang et al., 2012), and the mitochondrial apoptotic pathway (Akaike et al., 2010), nicotine can also protect neurons from oxidative stress-induced apoptosis

in rapid succession (Figure 1)

The lecithin is an extract of soy oil, not protein

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Contact with the round window membrane is maintained for 30 minutes by placing the animal in a recumbent position Intratympanic injectionEach animal is positioned so that the head is tilted at an angle to favor injection towards the round window niche