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The most impactful upcoming change: if the BALANCE model transitions to permanent Medicare Part D coverage in 2028 as planned, approximately 50 million Medicare beneficiaries will gain access to GLP-1 for obesity treatment

Many patients notice improved healing within the first few weeks of treatment

Peptides can stimulate the secretion of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH)

Oral GLP-1 medications are also available, although they are less effective in promoting weight loss

Increase exercise intensity and volume if your body is ready

The proteomic signature of semaglutide could possibly serve to assess intentional and nonintentional nonadherence with prescribed treatment, especially in those with modest weight loss 47