Common GLP-1 side effects often include nausea, constipation, diarrhea, vomiting, reflux, abdominal discomfort, reduced appetite, and fatigue
Long-Term Weight Loss and Metabolic Health Benefits Over multiple months of continuous dosing, participants in clinical trials exhibited improved insulin sensitivity, reduced blood sugar, lower blood pressure, and enhanced metabolic health markers
Taking with food reduces these effects significantly
Patients with pre-existing severe gastrointestinal conditions, including gastroparesis, should discuss these with their prescriber before starting GLP-1 medications
These medications change the hunger signals in your brain, reducing your appetite and making you feel full faster (5)
When taking weight loss medications like retatrutide, watch for the following symptoms: Sharp pain in the upper right abdomen, which may worsen after fatty meals Pain radiating to the back or right shoulder blade Nausea or vomiting Fever with chills If these symptoms occur, consult your healthcare provider for proper diagnosis and treatment and stop taking the medication