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En octubre del 2025 la FDA amplio la indicacin de simaglutida para la reduccin del riesgo de eventos cardiovasculares mayores (muerte cardiovular, infarto al miocardio no fatal, ataque vascular no fatal) en adultos con diabetes mellitus tipo 2 (no insulinodependiente) que tienen riesgo alto de desarrollar estos eventos

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This glucose-dependent mechanism offers the benefit of avoiding hypoglycemia, while simultaneously contributing to effective glycemic control [71]