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References 1 Acosta-RodrguezV.Rijo-FerreiraF.GreenC.TakahashiJ

Testing also makes insurance far more likely to cover injections, because coverage typically hinges on lab results that document a deficiency

1,2 Although not clinically validated or available for widespread use, measurement of holotranscobalamin, the metabolically active form of vitamin B 12 , is an emerging method of detecting deficiency

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Chronic exposure exacerbates these symptoms through mechanisms, such as oxidative stress, excitotoxicity, and mitochondrial dysfunction, in the nigrostriatal pathway (Graves et al., 2021), leading to progressive motor slowing and postural instability