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Considering the complex role of Wnt signaling in disc development and degeneration, it is needed to clarify the exact roles and determinants of these Wnt inhibitors in IVDD (85)

Crohns Disease causes inflammation of the wall of the gastrointestinal (GI) tract

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Animals began the study on a diet containing 2% EtOH (v/v) (10.8% EDC) and the amount of EtOH was increased 1% weekly until it reached 5% (v/v) (26.9% EDC) and the animals were maintained on 5% EtOH (v/v) for the remainder of the study