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Another network meta-analysis of RCTs, including participants with T2DM, found that GLP-1 RAs decreased the risk of non-fatal MI (Odds Ratio [OR] = 0.92, 95%CI = 0.850.99) when compared to placebo or standard care ( Unstable angina pectoris: An umbrella review of meta-analyses of RCTs including 56,004 patients with diabetes, prediabetes, and at high risk of diabetes, found no association between GLP-1 RAs and the risk of uAP (RR = 1.06, 95%CI = 0.931.21) when compared to placebo (Zhu et al., 2020)

Both excesses and deficiencies of certain nutrients, as well as exposure to heavy metals, toxins, and endocrine disruptors, can disrupt immune tolerance

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