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Supported, though it travels with the two above rather than standing alone

For the 5 mg/kg IP injection, the estimated mean AUC by 3 h (AUC 03hr ) was 20.4 mgmin/mL, which accounted for more than 95% of the estimated total AUC (AUC 0- ) of 21.0 mgmin/mL

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The severity varies considerably between individuals, with some experiencing mild infrequent bowel movements and others developing significant discomfort requiring intervention

Food & Drug Administration (FDA-d)