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Amyotrophic lateral sclerosis associated disturbance of iron metabolism is blunted by swim training-role of AKT signaling pathway

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Published mechanisms include upregulation of growth hormone receptor expression, promotion of angiogenesis via VEGF pathway activation, modulation of the nitric oxide system, and interaction with the dopaminergic and serotonergic systems in neurological models

These nerve fibers release neuropeptides that trigger the production of inflammatory mediators such as cytokines, and prostaglandins, which activate nociceptive pathways (174)

doi: 10.1210/en.2006-0640 113 TaoYLiZYangYJiaoYQuJWangYet al