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It is naturally synthesized within the cytosol of almost every cell in the body, with the highest concentrations found in the liver, lungs, and brain

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Most studies have been conducted in rodent models, and while results are overwhelmingly positive, we cant yet predict how chronic or high-dose use will affect humans over time

[DOI: 10.1016/S2665-9913(20)30121-1] [DOI] [PMC free article] [PubMed] [Google Scholar] 16.Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Taylor Thompson B, Marco Ranieri V