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Laboratory/In-Vitro Experimental Use Only.

All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA)

Basic information Price Properties Safety Description Related Supplier More related my chemicalbook En ChemicalBook CAS DataBase List Dihexa Dihexa $69 - $3087 Product name Dihexa Cas No 1401708-83-5 MF C27H44N4O5 MW 504.66 EINECS 227-005-2 MDL Number MFCD30533409 Synonyms Dihexa;N-hexanoic-Try-Ile-(6)-amino hexanoic amide;Dihexa (PNB-0408);N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-L-ISOLEUCINAMIDE;L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;TIANFUCHEM--1401708-83-5---Dihexa;Prebiotic dipeptide;N-hexanoic-Tyr-Ile-(6) aminohexanoic amide show less show more Price 43 prices Brand less more Cayman Chemical aablocks Arctom ACHEMBLOCK ChemScene DC Chemicals AK Scientific Biosynth Usbiological Medical Isotopes, Inc

50 & Target Kd: 65 pM (HGF) [1] In Vitro Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering

Metabolite production was quantified by LC/MS/MS API3000 and normalized to total cell protein

In organotypic hippocampal slice cultures, Dihexa and Nle-AngIV similarly augmented spinogenesis, with control slices showing 7 spines per 50-m dendrite length, compared to 11 for both Dihexa and Nle-AngIV treated slices [1]