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Since central nervous system (CNS) penetrance is of utmost importance for ASD therapeutics, it is especially necessary to evaluate delivery methods that have higher efficiency in crossing the blood-brain barrier (BBB)
You may be asking why
Liu ML, Ylitalo K, Salonen R, Salonen JT, Taskinen MR
NOT approved by FDA for human use
They found that in people with autism, the drug boosts brain levels of gamma-aminobutyric acid (GABA), which dampens brain signals, relative to levels of glutamate, which excites brain activity
How three receptors work together Each receptor contributes something different to the overall effect: GLP-1 receptor activation: Reduces appetite, slows gastric emptying, and enhances insulin secretion
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