(1992, Biochem J) demonstrated that IGF-1 and its variants including Long R3 IGF-1 are anabolic in dexamethasone-treated rats, confirming the utility of IGF-1 LR3 in models of catabolic states and muscle wasting where native IGF-1 activity is suppressed by glucocorticoid-driven IGFBP upregulation
(PubMed) There is also a more basic issue: even when these studies report health or survival benefits, they do not establish that the benefit was driven specifically by telomere extension
However, evidence directly applicable to musculoskeletal clinical outcomes remains limited
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I have written extensively about mycotoxins and their impact on specific body systems
These are often used in conjunction with physiotherapy rehabilitation and other medications for a more lasting cure of many conditions, such as subacromial impingement syndrome, AC joint pathology and inflammatory arthritides
