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In fibroblast cultures, it has been shown to modulate expression of a large number of genes involved in repair and antioxidant defense

In some embodiments, a trophic effect is desirable during otic surgery or during intratympanic injection procedures

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On Day 2, the medium was switched to RPMI/B27-Insulin with Activin (100 ng/mL) and Hepatocyte Growth Factor (HGF, 20 ng/mL)

However, these data have not yet been the subject of a complete publication in a peer-reviewed journal, and the sample size remained modest