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Diabetes medications (e.g., insulin, metformin) to control blood sugar

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All three medications require ongoing prescriber oversight , including regular consultations (often monthly or quarterly), which incur additional fees ranging from 50 to 150 per appointment

Multivariate analysis To identify microbiota composition differences between individuals split in TMAO clusters we performed multivariate homogeneity analysis of BrayCurtis dissimilarity matrices at the species level (699 species present in at least 20% of our population) and determined statistical significance with a permutation ANOVA test (999 iterations) using the vegan (v2.5.7) package

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