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Tripp A, Kota RS, Lewis DA, Sibille E (2011)

JCEM Case Rep 2023;1(1):luac004

While GLP-1RAs demonstrate immunomodulatory potential relevant to SS pathogenesis through their effects on key immune cell populations, direct experimental evidence characterizing their impact on SS-specific immune dysregulation remains strikingly limited

Recent advancements in sustained-release formulations, like PLGA nanoparticles for delivering exendin-4, show promise in preclinical models but still require validation in human studies (Wang et al., 2023)

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Because collagen has been shown to support healthy inflammatory responses, taking it during this phase may help manage the general "achy" feeling that often accompanies a period