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The TfR1s primary role is generally considered to be maintaining cell iron homeostasis

Annals of Clinical Biochemistry , 2000, 37: 627-648

The observation of other anxiety-like behavioral activity in the open field test revealed that the MSG group tended to visit the central zone less often than the control group did, as indicated by the number of crossings ( P 0.05)

This redox capability is fundamental to many of its medical applications, including treating methemoglobinemia by converting ferric ions in hemoglobin to ferrous ions

Its role in research is exploratory and focused on mechanistic understanding, rather than producing therapeutic outcomes

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