GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists strengthened warnings on acute pancreatitis including necrotising and fatal cases
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In all of these cases, the appropriate response is medical evaluation rather than discontinuing tirzepatide, which is unlikely to be the cause and is probably helping through its metabolic benefits
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To further confirm the cell death pathways that ALDH2 may affect, we used different concentrations of the ferroptosis agonists erastin and RSL-3, the apoptosis agonist staurosporine, and the autophagy agonist rapamycin to stimulate SH-SY5Y cells for 24 h
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